A team of researchers has conducted Alzheimer’s-related study at The University of Chicago, which is recently published in the Journal of Experimental Medicine. They explained how long-term use of a combination of antibiotics influenced alterations in the gut microbiome of mice to an extent that it retarded the growth of amyloid plaques, specifically in males mice.
Amyloid plaques usually develop when a specific protein within the brain neurons accumulates and form clumps. These plaques interrupt brain cell functioning and initiate the symptoms of Alzheimer’s.
Through the earlier researches and studies, the researchers were familiar with the association of Alzheimer’s and gut microbiome changes. However, in recent research, they found that variations in the microbiome restricted the growth of amyloid plaques limited was gender specific.
The team found that in the case of female mice, the gut microbiome changes influenced the immune system by increasing the production rate of factors that could stimulate the activation of microglia. This did not occur in male mice.
To verify their results, the team conducted in-vitro trials on mice and found that re-establishment of gut microbiome led to an increased formation of amyloid plaque formation and activation of microglia in females.
On a similar note, according to novel research conducted at the University of Sherbrooke, Quebec, a drink derived from coconut oil be used to protect humans from the memory loss effects associated with dementia and Alzheimer’s disease.
The study was published this month in the journal Alzheimer’s & Dementia, which proposes that the brain of elders with mild cognitive disabilities could consume ketones, developed inside the body to combat such memory problems.
The researchers specified that with the aging the efficiency of brain cells to deliver energy in the form of fuel begins to reduce significantly. Therefore, this problem can be overcome by supplying the ketones as a substitute for glucose.
The researchers conducted a trial on 52 seniors with mild cognitive disabilities. In a six-month trial period, the participants were given a liquid dietary supplement on a daily basis comprising either 30 Grams of medium-chain triglycerides (MCTs) or placebo. After the trials, several word recognition, memory-related, and processing speed-related tests were conducted, in which MCTs-consuming participants scored better.
Chad has studied masters in biochemistry and is a content editor at our portal. He is having sound knowledge about molecular biology. In free time, he likes to read and write articles on human health care. Chad is associated with us from last 5 Years; formerly he has worked with one of the leading publishers in the industry. He likes to play chess and believes that it helps him in stress-busting and focusing in day to day life.